Top 10 AI agent startups from Y Combinator's first spring Demo Day

Y Combinator's first-ever spring cohort featured 70 startups focused on agentic AI, with Demo Day showcasing their innovative technologies. The intensive three-month accelerator program invests $500,000 in each selected startup, continuing YC's legacy of nurturing successful companies like Stripe, Airbnb, and Instacart.

Key Highlights:

• 70 of 144 startups in the spring 2025 batch build AI agents
• YC partners prioritized creative applications of AI across industries
• Startups span healthcare, fintech, cybersecurity, and robotics

Top 10 AI Agent Startups:

1. Aegis

   • Focus: Automates insurance appeals for healthcare providers
   • Founders: Krishang Todi, Aarav Bajaj, Dhanya Shah
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2. Airweave

   • Focus: Turns productivity tools into searchable AI agent databases

3. Approval AI

   • Focus: Automates mortgage processes from rate shopping to paperwork
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4. Atlog

   • Focus: AI voice agents for furniture rental sales calls

5. Beluga Labs

   • Focus: Financial organization for content creators
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6. Casco

   • Focus: Simulates attacks on AI systems to find vulnerabilities
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7. Galen AI

   • Focus: Personalized health advice from wellness data
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8. Mbodi AI

   • Focus: Teaches new skills to existing robots
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9. Plexe

   • Focus: Open-source agents for predictive ML models
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10. Willow

    • Focus: Voice dictation with tone-matching AI
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For more on AI startups, see Business Insider's coverage.

The spring 2025 batch marks Y Combinator's expansion to two annual cohorts, with a clear emphasis on practical AI applications across diverse sectors.