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Top 10 AI agent startups from Y Combinator's first spring Demo Day

June 11, 2025•Samantha Stokes•Original Link•2 minutes
AI
Startups
YCombinator

Y Combinator's inaugural spring cohort showcased 70 AI agent startups, with 10 standout companies revolutionizing industries from healthcare to fintech.

Y Combinator's first-ever spring cohort featured 70 startups focused on agentic AI, with Demo Day showcasing their innovative technologies. The intensive three-month accelerator program invests $500,000 in each selected startup, continuing YC's legacy of nurturing successful companies like Stripe, Airbnb, and Instacart.

Key Highlights:

  • 70 of 144 startups in the spring 2025 batch build AI agents
  • YC partners prioritized creative applications of AI across industries
  • Startups span healthcare, fintech, cybersecurity, and robotics

Top 10 AI Agent Startups:

  1. Aegis

    • Focus: Automates insurance appeals for healthcare providers
    • Founders: Krishang Todi, Aarav Bajaj, Dhanya Shah
    • Aegis co-founders
  2. Airweave

    • Focus: Turns productivity tools into searchable AI agent databases
  3. Approval AI

    • Focus: Automates mortgage processes from rate shopping to paperwork
    • Approval AI co-founders
  4. Atlog

    • Focus: AI voice agents for furniture rental sales calls
  5. Beluga Labs

    • Focus: Financial organization for content creators
    • Beluga Labs co-founders
  6. Casco

    • Focus: Simulates attacks on AI systems to find vulnerabilities
    • Casco co-founders
  7. Galen AI

    • Focus: Personalized health advice from wellness data
    • Galen AI co-founders
  8. Mbodi AI

    • Focus: Teaches new skills to existing robots
    • Mbodi AI co-founders
  9. Plexe

    • Focus: Open-source agents for predictive ML models
    • Plexe co-founders
  10. Willow

    • Focus: Voice dictation with tone-matching AI
    • Willow co-founders

For more on AI startups, see Business Insider's coverage.

The spring 2025 batch marks Y Combinator's expansion to two annual cohorts, with a clear emphasis on practical AI applications across diverse sectors.

Related News

August 18, 2025•Kaydence Shum

Lenovo Wins Frost Sullivan 2025 Asia-Pacific AI Services Leadership Award

Lenovo earns Frost Sullivan's 2025 Asia-Pacific AI Services Customer Value Leadership Recognition for its value-driven innovation and real-world AI impact.

AI
Lenovo
Asia-Pacific
August 18, 2025•Unknown

Baidu Wenku GenFlow 2.0 Revolutionizes AI Agents with Multi-Agent Architecture

Baidu Wenku's GenFlow 2.0 introduces a multi-agent system for parallel task processing, integrating with Cangzhou OS to enhance efficiency and redefine AI workflows.

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MultiAgent
Baidu

About the Author

Dr. Emily Wang

Dr. Emily Wang

AI Product Strategy Expert

Former Google AI Product Manager with 10 years of experience in AI product development and strategy formulation. Led multiple successful AI products from 0 to 1 development process, now provides product strategy consulting for AI startups while writing AI product analysis articles for various tech media outlets.

Expertise

AI Product Management
User Experience
Business Strategy
Market Analysis
Experience
10 years
Publications
65+
Credentials
2
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